Free Fatty Acids in VCO Nanoemulsion Formulation: Nutraceuticals for Colon Cancer

Authors

  • Muhammad Iqbal university of lampung
  • Ramadhan Triyandi university of lampung
  • Wawan Abdullah Setiawan university of lampung

Keywords:

nanoemulsion nVCO, colon cancer, free fatty acid

Abstract

Colon cancer ranks as the second leading cause of cancer-related deaths globally. Conventional treatments often cause numerous side effects and lack selectivity. Therefore, developing anticancer agents derived from virgin coconut oil (VCO) nanoparticles has become a promising approach in cancer drug discovery. This study investigates the anticancer potential of VCO nanoemulsion (nVCO) for colon cancer by analyzing its free fatty acid composition. Characterization of nVCO was performed using Gas Chromatography–Mass Spectrometry (GC-MS). The findings revealed that the nVCO formulation met the criteria for a nanoemulsion. The free fatty acid content of nVCO was 0.9%, and GC-MS analysis identified lauric acid at 4,29%. Understanding the anticancer mechanism of VCO is crucial, given that colon cancer cells exhibit diverse characteristics. This research offers scientific support for the development of VCO nanoparticles as a safe, natural nutraceutical innovation for colon cancer therapy based on free fatty acid.

Keywords: nanoemulsion, nVCO, colon cancer, free fatty acid

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Published

2025-12-19

How to Cite

Iqbal, M., Triyandi, R., & Abdullah Setiawan, W. (2025). Free Fatty Acids in VCO Nanoemulsion Formulation: Nutraceuticals for Colon Cancer. ICSIGER- International Conference on Science and Emerging Technology , 1(1). Retrieved from https://conference.lppm.unila.ac.id/index.php/icsiger/article/view/212

Issue

Vol. 1 No. 1 (2025): Proceedings of The International Conference on Science and Emerging Technology (ICSIGER)

Section

Articles